The possibility of kidney damage when treating high blood pressure

A new Canadian study published on 9/11 showed that patients who regularly use calcium channel blockers should not use it in combination with clarithromycin antibiotics because this combination may lead to Rare but serious kidney damage.

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Dr. Amit Garg, author of the study, said that over the past decade, the Ontario Department of Health has recorded nearly 100,000 prescriptions combining these two drugs for high blood pressure and antibiotics despite warnings. given.

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The researchers compared the proportion of patients who were hospitalized with acute kidney damage , lowering blood pressure and death of those who used high blood pressure blockers to block calcium channels with other antibiotics, not clarithromycin. .

Research has found that the number of people using clarithromycin antibiotics with calcium channel blockers has a higher risk of acute kidney injury, lowering blood pressure and death within 30 days of starting. use antibiotics.

Calcium channel blockers include amlodipine, sold with Norvasc, nifedipine (Adalat), felodipine (Plendil), diltiazem (Cardizem) and verapamil (Isoptin). Clarithromycin is also sold under the Biaxin brand.

Dr. Garg said that the results of the study showed that there is a possibility that hundreds of patients will be hospitalized and died in Ontario province mainly related to this drug interaction.

Data from other regions of the world also show the unwise combination of the two drugs.

Earlier this year, researchers at the Lawson Medical Research Institute, Ontario province, and the Toronto Clinical Research Institute also published a study showing clarithromycin and another antibiotic, erythromycin, are similar. Dangerously working with statin drugs to lower cholesterol.