Why do people with good pain and sufferers suffer?

The genetic difference, the body experience can be the whole cause for each of us to feel different pain.

Pain is the body's natural reaction to an external impact or internal injury that "reports" the need to seek medical attention. Under normal circumstances, this natural reaction protects the body until the damage recovers and the pain subsides.

However, the same impact but each person felt different pain . Their bodies will also react differently to pain. This makes it difficult to diagnose and treat medical treatment.

Dr. Gila Moalem-Taylor, senior lecturer at the University of New South Wales (UK) said: "Pain threshold determines the degree to which we feel a painful stimulus. It all begins to affect at the receptor receptors for pain (nociceptor) They are converted into pain signals then transmitted throughout the central nervous system through a series of "pain pathways".

Each person has different feelings for pain - (Photo: BBC).

"There is a" path "that goes from the periphery (skin) into the cells in the lymph nodes and spine. From there, the pain is transmitted to the brain," explains Moalem-Taylor .

Each individual will have a different manifestation when the receptor receptor receives pain begins signaling. In each class that information passes, there may be some adjustment effects that reduce or increase the level of pain sensation.

Another explanation is due to genetic differences .

Human genes have different genetic variations that make the difference between one person and another. Most of the variations that make up the difference are single nucleotide polymorphisms (SNPs) .

There are about 10 million SNPs known in the human genome. The combination of an individual's SNPs makes that person's DNA code. When a SNPs are popular, it is called a variant; when a SNPs are rare, occupying less than 1 percent of the population, it is called mutation.

The variation in gene variants is evidence that each person will have different feelings about pain.

Among the variations that make up the difference, SCN9A is the most remarkable gene. Very few people in the world have SCN9A genes . When carrying this gene, the person will completely lose the feeling of pain or feel too sensitive to the pain.

Not seeing pain is not a great thing, because the person will not detect bodily injuries. A person with a SCN9A gene will not experience a heart attack, nor does he know that he has appendicitis, cannot receive medical treatment in time, and may lose his life right before they realize the problem.

Currently, scientists are still in the process of investigating this issue to create more effective methods of pain relief in medical treatment and to understand "why pain" and not just "where does it hurt? ".

•