Red wine compound Resveratrol is very beneficial for health

The benefits of alcoholic beverages are tied to the dose. Moderate to moderate levels - especially for red wine - will help reduce any cause of death. Meanwhile, drinking too much will cause many agencies to be harmed.

An article summarizing the recent findings on polyphenols of red wine, especially resveratrol, will be published in the September issue titled Alcohol Harm: Experimental and Bright Studies, The article is also published in Early View.

Lindsay Brown, an associate professor at the University of Queensland School of Biomedical Sciences and author of the study's response, said: 'Articles about the benefits of red wine have been around for nearly two decades. . Mass media created a closer story of the French paradox in the early 1990s. However, studies of the effects of resveratrol - one of the active ingredients - are unknown. until research conducted in 1997 showed that it had a preventative effect on cancer. This raises a great concern for this compound '.

Red wine contains a complex mixture of bioactive compounds, including flavonol, monomeric and polymeric flavan-3-ols, anthocyanins, phenolic acid and resveratrol. Brown said some of these compounds, especially resveratrol, are beneficial to health.

"Its benefits are significant, it helps prevent cancer, protects the heart and brain, reduces age-related diseases such as inflammation, diabetes, obesity and many other diseases, " Brown said . . It has long been questioned why such a simple compound has such great effects, but the answer is gradually evident with the discovery of the way in which the sirtuin enzyme applies to regulation. The process of producing cellular components through multiplication. Is resveratrol the only compound that carries these characteristics? It doesn't seem like that. Other compounds in wine and natural products like curcumin also have similar effects. However, we know resveratrol more than other compounds'.

Stephen Taylor, a professor of pharmacology at the University of Queensland, agrees that resveratrol is the 'compound of the day'. He said: 'I think red wine is both mystical and historical symbol in the west. Of course some pleasures must be associated with drinking wine, all of which have psychological benefits for people. Not many of us can or will eat a few cups of cranberries every day for many years, but if we do a study in a decade then they will have the same effect. '

The main features in the summary article include:

Resveratrol has therapeutic potential for cancer prevention as well as cardiovascular protection.

Low or moderate alcohol consumption - especially for red wine - will help reduce any cause of death. (Photo: iStockphoto)

Brown said: 'It sounds contradictory to say that a compound can also protect the heart by preventing cell damage, but preventing cancer by causing cells to die. The most appropriate explanation for it is still being studied to prove in many organs. Low concentrations have triggered cell survival mechanisms while high concentrations signal the self-destruction of these cells.

Resveratrol supports the prevention of age-related disorders , such as memory problems, inflammation, diabetes and cardiovascular disease.

According to Ms Brown, 'the simplest explanation is that resveratrol signals the cell's survival pathway, preventing cell damage. New measures will support resveratrol, including the elimination of reactive oxidants in the body and increased blood supply to cells'.

Low doses of resveratrol may increase cell survival, a way to protect the nerves as well as the heart; while high doses cause cells to die.

'The key difference is probably the result of activating the sirtuin enzyme family in the nucleus. Low-level activation reverses age-related changes, while high-level activation promotes cyclical cell destruction. Similar changes have been observed in the use of low-dose and high-dose resveratrol: low doses help protect cells, reduce damage; High doses prevent cancer '.

Modern scientific studies are also beginning to explain reports over the past 200 years that drinking wine improves health. 'It is said that nature is a treasure of compound, but research with resveratrol has proven that it is true. We need to understand more about the types of compounds that exist in nature as well as to determine their potential for health. '

Taylor added: 'There is a special point that needs to be added. Resveratrol is largely eliminated by the intestine or liver before it reaches the bloodstream, where it is effective. Therefore, most resveratrol in drinking wine does not reach the circulatory system. Interestingly, absorption through the mucous membranes in the mouth can be nearly 100 times stronger than the level of blood if we sip slowly but not drink gulping. Of course we are not sure how important it is to drink, but things like this are completely true while most of us are indifferent. '

Refer:
Brown et al.The Biological Responses to Resveratrol and Other Polyphenols From Alcoholic Beverages.Alcoholism Clinical and Experimental Research, 2009;DOI: 10.1111 / j.1530-0277.2009.00989.x